The Hidden Harmony & Homeostasis

[Diagram of blood-insulin and blood-sugar levels over the course of a day, from the Wikipedia article on Blood Sugar]

Dear Reader,

The hidden harmony is present but often easy to overlook in the realms of math, physics, and chemistry, but biology demands an intuitive understanding of it because living systems exhibit all kinds of behavior that at first seems to contradict the rules and principles of these foundational sciences.

For example, consider the second law of thermodynamics (In a system, a process that occurs will tend to increase the total entropy of the universe, or, things tend to run from order to chaos, tend to run down, always increasing the unverse's entropy). It nicely explains aging, disease, and death but seems contradicted by conception, embryogenesis, evolution, and development (not to mention the Big Bang itself). Someone steeped for decades in the "hard sciences," when confronted inescapably by large-scale biology's many seeming contradictions of the hard-science principles, can either (1) turn away from biology and back to their more comfortable fields, (2) resort to miracles for explanation, or (3) search for additional cosmic principles that contradict principles like entropy, that wind things up instead of winding them down.

The second form of fluxus quo, the hidden harmony, intuitively explains what the second law of thermodynamics, entropy, does not—the capacity of living things to run from chaos to order, to wind up, to decrease an organism's entropy by unfolding layers of increasing order. The self-assembly of living systems is a miracle from the perspective of entropy but inevitable from the perspective of the hidden harmony.

In its simplest, easiest-to-explain form, the hidden harmony manifests in the ways living organisms work to maintain steady temperatures, or blood pressures, or access to glucose, or so on. This quality of living things, called homeostasis, produces what at first seem to be comparatively steady states through the harnessing and control of opposing forces.

One example of this is the way insulin and glucagon set in motion opposing tendencies with regard to the regulation of blood-sugar levels. When they rise too high, a healthy pancreas releases insulin to instruct cells to absorb more glucose from the blood, thus lowering the blood glucose levels. When they fall too low, the pancreas releases glucagon to instruct the liver to convert more glycogen into glucose and release it into the blood, thus raising blood glucose levels. Over the course of a day, blood-glucose levels are almost never at a steady state, never a status quo; rather they are always rising and falling in response to digestion and the cells' consumption of blood glucose, and when those cycles spike erratically from the consumption of sugar or from excessive energy demands the body intervenes with insulin or glucagon to channel them back into the narrow band of blood-sugar levels that supports human health.

Living systems are densely woven with such homeostatic systems for preserving an organism's health, as is the cosmos itself, since we evolved to be healthy within the normal conditions of our environmental niches.

[Photo of James Heilman juggling from Wikipedia article on Juggling]

In all these cases, the appearance of stasis is an illusion; both forms of dynamism are always in operation. First, there will be a cosmic river—an overt flow of materials and energies upon which life depends. Second, there will be a hidden harmony—two or more primary systems set in opposition to channel, set in motion, and modulate that cosmic river, and many secondary systems that stabilize and reinforce the primaries.

With all this flux going on, it shouldn't be called homeostasis. It should be called homeoflux.

Like juggling, any apparent steady state is actually a state of continual change (the moving balls) that is itself driven by a more fundamental underlying pattern of change (gravity, mass, and the juggler). If, for fear of dropping the balls or making a mistake the juggler tried to just hold them still, the act of juggling would be at an end, the episode of juggling would die, because in a truly living system it is the fluxus quo that produces what we think of as the life within the system.

So it is with the human body. The flow of blood, lymph, cerebrospinal fluid, air, food, water, hormones, nerve impulses, chemical reactions triggered by photons striking the skin, the flowing transformation of biochemicals along metabolic pathways, and many many other things beside, the flow of all these things must continue for our life to continue. Stop even one of these flows, and sooner or later we sicken and die. The body is not flesh at all but is instead a flow, a nexus, a crossroad of many rivers, and we die when the rivers stop flowing through us, when they go their own ways and leave us in an apparent status quo (although the truth is that we go on flowing in different ways after we die, as we dissolve into the tributaries of other rivers).

So it is with managing VISTA. The effort to control VISTA, to hold it tightly, to decide what will and will not get worked on, these efforts kill a VISTA adoption. All of the elements of the VISTA model have to actually flow channeled but unimpeded to create a homeostatic VISTA system capable of supporting a hospital. A VISTA lifecycle is a living system, a form of nonorganismic life, in which the flow must go on; thirty years of experiments with the alternatives have proven the truth of this to anyone who has bothered to learn from its history.

At this point, if you don't feel comfortable with the fundamentals of fluxus quo, I'm gong to say the burden is on you now to ask about it. Fluxus quo is one of the essential principles that makes VISTA work, but as for what must flow and how—the fundamentals of its health, to succeeding with VISTA adoption—well, the devil's in the details, and it's time to talk about them.

Let's move now from the principle to its manifestations. Let's explore some of the homeostatic systems that must function correctly for the production, development, and maintenance of VISTA.

Yours truly,
Rick